Explainable AI

Deep learning models are often regarded as black boxes, but this limits the ability to trust the decisions they make. Thus, methods are needed to enable understanding of the mechanisms behind the decision making process.

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Papers

Prototype Learning for Explainable Regression
Linde S Hesse, Nicola K Dinsdale , Ana IL Namburete
IEEE/CVF Winter Conference on Applications of Computer Vision (WACV), 2023
Paper / Code

In this work we present ExPeRT: an explainable prototype-based model specifically designed for regression tasks.

Characterizing personalized neuropathology in dementia and mild cognitive impairment with explainable artificial intelligence
Esten H. Leonardsen, Karin Persson, Edvard Grødem, Nicola K Dinsdale , ... , Thomas Wolfers, Lars T. Westlye, Yunpeng Wang
npj Digital Medicine, 2024
Paper

We trained convolutional neural nets to differentiate patients with dementia from healthy controls, and applied layerwise relevance propagation to procure individual-level explanations of the model predictions. Through extensive validations we demonstrate that patterns recognized by the model corroborate existing knowledge of neuropathology in dementia.

Challenges for machine learning in clinical translation of big data imaging studies
Nicola K Dinsdale , Emma Bluemke, Vaanathi Sundaresan, Mark Jenkinson, Steve Smith, Ana IL Namburete
Neuron , 2022
Paper / Code

Review article, explores: data availability, interpretability, model bias and data privacy.

Learning patterns of the ageing brain in MRI using deep convolutional networks
Nicola K Dinsdale , Emma Bluemke, Steve Smith, Zobair Arya, Diego Vidaurre, Mark Jenkinson, Ana IL Namburete
Neuroimage, 2021
Project Page / Paper / Code

Development of age prediction model using data from the UK Biobank, and exploration of correlations with UK Biobank Variables. We also explore the effect of registration on the model.


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